7SL RNA

7SL RNA is an RNA molecule, component of the signal recognition particle (SRP).

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Although originally the SRP was thought to be only composed by 6 polypeptides, this small cytoplasmic RNA molecule was found to be a component of the complex.

The RNA gene for 7SL is transcribed by the RNA polymerase III.

The common SINE family Alu probably originated from a duplication of a 7SL RNA gene.

See also

• Eukaryotic type signal recognition particle RNA
• Bacterial signal recognition particle RNA

References

• Walter P, Blobel G. "Signal recognition particle contains a 7S RNA essential for protein translocation across the endoplasmic reticulum.", Nature 21;299(5885):691-8 (1982).