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Phosphoglycerate kinase



phosphoglycerate kinase 1

Enzyme Phosphoglycerate kinase
PDB Code PDB 3PGK
Organism Yeast
Symbol(s): PGK1
Genetic data
Locus: Chr. X q13.3
Database Links
EC number: 2.7.2.3
Entrez: 5230
OMIM: 311800
RefSeq: NM_000291
UniProt: P00558
phosphoglycerate kinase 2
Symbol(s): PGK2
Genetic data
Locus: Chr. 6 p21-q12
Database Links
Entrez: 5232
OMIM: 172270
RefSeq: NM_138733
UniProt: P07205

Phosphoglycerate kinase is a transferase enzyme used in the seventh step of glycolysis.

It transfers a phosphate group from 1,3-biphosphoglycerate to ADP, forming ATP and 3-Phosphoglycerate.

This metabolism related enzyme article is a stub. You can help Wikipedia by expanding it.
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Glycolysis Metabolic Pathway
Glucose Hexokinase Glucose-6-phosphate Phosphoglucoisomerase Fructose 6-phosphate Phosphofructokinase Fructose 1,6-bisphosphate Fructose bisphosphate aldolase Dihydroxyacetone phosphate Glyceraldehyde 3-phosphate Triosephosphate isomerase Glyceraldehyde 3-phosphate Glyceraldehyde phosphate dehydrogenase
ATP ADP ATP ADP NAD+ + Pi NADH + H+
+ 2
NAD+ + Pi NADH + H+
1,3-Bisphosphoglycerate Phosphoglycerate kinase 3-Phosphoglycerate Phosphoglycerate mutase 2-Phosphoglycerate Enolase Phosphoenolpyruvate Pyruvate kinase Pyruvate Pyruvate dehydrogenase Acetyl-CoA
ADP ATP H2O ADP ATP CoA + NAD+ NADH + H+ + CO2
2 2 2 2 2 2
ADP ATP H2O
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Carbohydrate metabolism: glycolysis/gluconeogenesis enzymes
GlycolysisGlucokinase/Hexokinase/Glucose 6-phosphatase - Glucose isomerase - Phosphofructokinase 1/Fructose 1,6-bisphosphatase - Aldolase - Triosephosphate isomerase - Glyceraldehyde 3-phosphate dehydrogenase - Phosphoglycerate kinase - Phosphoglycerate mutase - Enolase - Pyruvate kinase
Gluconeogenesis onlyPyruvate carboxylase - Phosphoenolpyruvate carboxykinase - from lactate (Cori cycle): Lactate dehydrogenase - from alanine (Alanine cycle): Alanine transaminase
RegulatoryPhosphofructokinase 2/Fructose 2,6-bisphosphatase - Bisphosphoglycerate mutase
v • d • e
Phosphotransferases/kinases (EC 2.7)
2.7.1 - OH acceptorHexo- - Gluco- - Fructo- (Hepatic fructo-) - Galacto- - Phosphofructo- (1, 2) - Thymidine - NAD+ - Glycerol - Pantothenate - Mevalonate - Pyruvate - Deoxycytidine - PFP - Diacylglycerol - Bruton's tyrosine - Phosphoinositide 3 (Class I PI 3, Class II PI 3) - Sphingosine
2.7.2 - COOH acceptorPhosphoglycerate - Aspartate
2.7.3 - N acceptorCreatine
2.7.4 - PO4 acceptorPhosphomevalonate - Adenylate - Nucleoside-diphosphate
2.7.6 - P2O7Ribose-phosphate diphosphokinase - Thiamine pyrophosphokinase
2.7.7 - nucleotidyl-Integrase - PNPase - Polymerase - RNase PH - UDP-glucose pyrophosphorylase - Galactose-1-phosphate uridylyltransferase -Terminal deoxynucleotidyl transferase - RNA replicase - Reverse transcriptase (Telomerase) - Transposase
2.7.8 - other phos.N-acetylglucosamine-1-phosphate transferase
2.7.10-11 - proteinTyrosine - Serine/threonine-specific
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Phosphoglycerate_kinase". A list of authors is available in Wikipedia.
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