2C-F

2C-F, or 4-fluoro-2,5-dimethoxyphenethylamine, is a lesser-known psychedelic drug of the 2C family. It was first synthesized by Alexander Shulgin. In his book PIHKAL (Phenethylamines I Have Known and Loved), the minimum dosage is listed as 250 mg. 2C-F may be found as a brownish freebase oil, or as a white crystalline hydrochloride salt.

Additional recommended knowledge

Daily Sensitivity Test

Daily Visual Balance Check

Essential Laboratory Skills Guide

Dosage and Effects

Very little data exists about the pharmacological properties, metabolism, and toxicity of 2C-F. At a dose of 250 milligrams, 2C-F produces modest closed-eye visuals accompanied by lethargy ^[1]. The amphetamine analogue DOF is likely to be more active than the phenethylamine derivative 2C-F, and in animal trials DOF was found to be 1/6th the dosage of the potent hallucinogen DOI, which would make an active dose of DOF likely to be in the 6-18 milligram range, although it is not known to have been tested in humans.

References