2-Methyl-3,3-diphenyl-3-propanolamine


2-Methyl-3,3-diphenyl-3-propanolamine
Systematic (IUPAC) name
3-amino-2-methyl-1,1-di(phenyl)propan-1-ol
Identifiers
CAS number	33887-05-7
ATC code	?
PubChem	26538
Chemical data
Formula	C₁₆H₁₉N O
Mol. mass	241.33 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status	Legal
Routes	?

2-MDP is a dissociative anaesthetic drug which has been found to be an NMDA antagonist and produces similar effects to PCP in animals. The levo or (-) isomer is the active form of the drug.^[1]^[2]

Additional recommended knowledge

Daily Sensitivity Test

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References

^ Tang AH, Cangelosi AA, Code RA, Franklin SR. Phencyclidine-like behavioral effects of 2-methyl-3,3-diphenyl-3-propanolamine (2-MDP). Pharmacology, Biochemistry and Behaviour. 1984 Feb;20(2):209-13.
^ Blake JC, Davies SN, Church J, Martin D, Lodge D. 2-Methyl-3,3-diphenyl-3-propanolamine (2-MDP) selectively antagonises N-methyl-aspartate (NMA). Pharmacology, Biochemistry and Behaviour. 1986 Jan;24(1):23-5.

v • d • e Dissociative hallucinogens
2-MDP - Dexoxadrol - Dextromethorphan - Dizocilpine - Efavirenz - Enadoline - Esketamine - Etoxadrol - Ketamine - Nitrous oxide - PCE - PCP - PCPy - Salvinorin A - Pentazocine - TCP - Tifluadom - Tiletamine - Xenon