2,5-Dimethoxy-4-ethylamphetamine

DOET, HECATE, or 2,5-dimethoxy-4-ethylamphetamine is an analogue of DOM, and is the three-carbon chain homologue to 2C-E. It produces hallucinogenic, psychedelic, and entheogenic effects.

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Chemistry

DOET is in a class of compounds commonly known as alpha-methyl phenethylamines, or amphetamines and the full chemical name is 4-Ethyl-2,5-dimethoxy-alpha-methylbenzeneethanamine, or 1-(2,5-dimethoxy-4-ethylphenyl)propan-2-amine. It has an active stereocenter and (R)-DOET is the more active isomer.

Effects

DOET produces psychedelic and entheogenic effects that last up 14-20 hours. In his book PiHKAL, Alexander Shulgin lists a dosage of DOET as being 2-7 mg orally, with 6-7mg being the dosage for full, desired effects.

Pharmacology

The mechanism that produces the hallucinogenic and entheogenic effects of DOET is thought to result from its action as an agonist at the 5-HT_2A serotonin receptor.

Dangers

The toxicity of DOET is not known.

Legality

DOET is classified as a Schedule 1 substance in the United States, and is similarly controlled in other parts of the world. Internationally, DOET is a Schedule I drug under the Convention on Psychotropic Substances[1].

See also

• DOM
• PiHKAL

Categorization