2,4,6-Trichlorophenol

2,4,6-Trichlorophenol, also known as TCP, phenaclor, Dowicide 2S, Dowcide 2S, omal, is a chlorinated phenol that has been used as a fungicide, herbicide, insecticide, antiseptic,^[1] defoliant, and glue preservative.^[2] It is a yellow solid with a strong, sweet odour. It decomposes on heating to produce toxic and corrosive fumes including hydrogen chloride and chlorine.

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It is carcinogenic in animals, causing lymphomas, leukemia, and liver cancer via oral exposure.^[3][4] It is classified as Group B2 (probable human carcinogen) by the United States Environmental Protection Agency.^[4] The technical grade of this substance may contain polychlorinated dibenzodioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and other contaminants.^[5]

2,4,6-trichlorophenol is an environmental pollutant that has been found in fresh water lakes such as the Great Lakes.^[6]

References

1. ^ Ogunniyi TAB, Oni PO, Juba A, Asaolu SO, and Kolawole DO (2000-01-05). "Disinfectants/antiseptics in the management of guinea worm ulcers in the rural areas". Acta Tropica 74: 33-38(6). doi:doi:10.1016/S0001-706X(99)00057-1.
2. ^ Safety data for 2,4,6-trichlorophenol. University of Oxford (2005-09-05). Retrieved on 2007-11-16.
3. ^ 2,4,6-Trichlorophenol. The Carcinogenic Potency Database Project, University of Berkeley (2007-10-03). Retrieved on 2007-11-16.
4. ^ ^{a b} 2,4,6 Trichlorophenol. United States Environmental Protection Agency (Jan 2000). Retrieved on 2007-11-16.
5. ^ 2,4,6-Trichlorophenol. IPCS (Nov 1998). Retrieved on 2007-11-16.
6. ^ TP Halappa Gowdal, John D Lock, and Ruth G Kurtz (Feb 1985). "A comprehensive study of risk assessment for a hazardous compound of public health concern" 24 (2). doi:10.1007/BF00285444. ISSN 0049-6979. Retrieved on 2007-11-16.