SpiroChem AG

SpiroChem is a Swiss CRO, headquartered in Basel, Switzerland.

Our service and products (libraries, SpiroKits, catalog compounds) help scientists accelerate drug discovery. In particular, we help medicinal chemists to improve ADME properties, explore novel chemical space, remove synthetic hurdles and anticipate drug attrition.

With cutting-edge know-how in drug design and proprietary process chemistry technologies, SpiroChem offers innovative chemical solutions to pharmaceutical, agrochemical, and life science companies of all sizes.

Operating from Basel, Switzerland, our clients are located worldwide.

SpiroChem is the world-leading chemicals company on the concept of bioisosterism.

In particular, we have established a leadership position on the highly sought-after field of conformationally-restricted molecules and the concept of bioisosterism. We offer bioisosteric replacements for a variety of functional groups, such as acids, amides, heterocycles, lipophilic groups and benzenes. In particular, we have developed scalable processes to bicyclo[1.1.1]pentane scaffolds and we can also provide many oxetanes, spirocycles and cubanes on scale.